Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gramnegative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.

Indications

Gastrointestinal infections caused by colistin sensitive bacteria, like E. coli, Haemophilus and Salmonella spp. in calves, goats, poultry, sheep and swine.

Contra-indications

Hypersensitivity to colistin.

Administration to animals with a seriously impaired renal function.

Administration to animals with an active microbial digestion.

Side Effects

Renal dysfunction, neurotoxicity and neuromuscular blockade may occur.

Dosage

For oral administration:

Calves, goats and sheep:Twice daily 2 g per 100 kg body weight for 5 – 7 days.

Poultry and swine:1 kg per 400 – 800 litres of drinking water or 200 – 500 kg of feed for 5 – 7 days.

Note: for pre-ruminant calves, lambs and kids only.

Withdrawal Times

For meat: 7 days.

Storage

Store below 25ºC, in a cool and dry place, and protect from light.

For Veterinary UseOnly , Keep out of reach of children